Millipore Milliflex Plus Manuale utente
User Guide
Milliex®Plus
VHP Resistant Pump
The life science business of
Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in
the U.S. and Canada.
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
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OK
START
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Millipore
VHP
ON
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2
1. Notice
The information in this document is subject to change without notice and should not be construed as a
commitment by Millipore SAS. Millipore SAS assumes no responsibility for any errors that may appear in this
document. This manual is believed to be complete and accurate at the time of publication.
2. Application
The VHP Resistant Milliex® PLUS Pump is designed to perform ltrations of samples inside an isolator.
The pump is compatible with the isolator environment. The housing and the external parts are VHP resistant.
3. Operator and Equipment safety
All employees who will operate and/or be near the Milliex® Plus Pump VHP must comply with the following:
• Read and understand the user guide of the pump before
using this pump. Failure to follow operating instructions
could result in user injury or damage to the instrument.
• Read and understand all maintenance instructions
in this user guide before performing maintenance on
the pump. Failure to follow instructions could result
in user injury or damage to the instrument.
• Any alteration of the pump from factory specication
may cause unsafe conditions, and will void the
product warranty.
• Any attempt to use the pump in a manner not specied
in this user guide may result in damage to the instrument,
operator injury, and will void the product warranty.
• Do not attempt to open and repair the pump. Service
should be performed by trained and authorized
personnel only.
• Place the pump on a clean, at, stable, horizontal
surface, away from any source of excessive heat
and close to an easily accessible, properly grounded
power supply outlet.
• The Milliex® Plus Pump VHP must be installed and
used in a clean and dry area.
• The product is not intended to be used in explosive
atmosphere.
• Do not expose the power supply to liquid. If this
happens, immediately switch o and disconnect the
pump from the power outlet, wipe up the liquid.
• Use only accessories and replacement parts designed for
the pump. Using accessories not designed for the pump
could result in user injury or damage to the instrument.
• When ltrating hazardous liquids, wear and use proper
protective clothing and equipment for the handling and
the disposal of the liquid to be ltrated.
• The system power cord is the main system disconnecting
device, and must be easily accessible at all times.
• To avoid damaging the power cord or the outlet, it is
recommended that you pull on the plug and not on
the cord to unplug the system from a wall outlet or
an electrical connector.
• Make sure the power cord is not a tripping hazard. Make
sure that it is not gripped too tightly at the plug, the
outlet or the point where it is connected to the system.
• Before use, check that the hoses are not unplugged,
folded, or damaged.
• In case of skin contact with the ltrated liquid, refer
to the safety datasheet of the ltrated liquid for rst
aid measures.
• Dispose the ltrated liquids according to local regulations.
• Do not use the Milliex® Plus Pump VHP to ltrate
ammable products.
• Before cleaning, shut down the Milliex® Plus Pump
VHP and switch o and disconnect the power supply
from power source.
• Use only the power supply (model FRA072-S24-4)
designed for the pump.
• The power supply must be connected to the earthing
system.
• The electrical installation must comply with local
standards, power supply voltage: 100–240 Volt AC,
50–60 Hz.
• Use an electrical surge protector to prevent damage
to the system.
• Milliex® Plus Pump VHP System is designed for
indoor use only.
• Use and storage temperatures
– The Milliex® Plus Pump VHP and/or its accessories
must be kept away from any heat source. Do not
expose the system to direct sunlight or to temper-
atures outside the ranges of values are given below.
– Use and storage temperatures are given below:
– Maximum relative humidity (storage and operation)
80% at temperatures up to 31 °C, then linear
decrease to 50% RH at 40 °C.
• System dismantling—WEEE directive:
In accordance with to the European Union
Directive 2012/19/EC on Waste Electric and
Electronic Equipment (WEEE), the presence
of this logo on the product indicates that it
should not be disposed of in the normal waste
stream but collected separately.
Go to millipore.com/weee for details on how to ensure
proper treatment of the product in dierent countries.
System operation System storage Altitude
10 to 40 °C 0 to 40 °C < 2000 m
3
4. System description
A. VHP Pump (MXPPLUVHP)
The Milliex® Plus VHP pump is composed of the following elements:
• The pump body
• The pump head with its protective cover (MXPHEAVHP)
• A lead to protect the pump when the pump head is not in place (to be used for assembling the pumps
with the manifold tray)
The pump comes with the following documents:
• User Guide PF12640
• Certicate of conformity for the pump (MXPPLUVHPCOQ) and the pump head (MXPHEAVHPCOQ)
Note: The VHP resistant pump (MXPPLUVHP) is compatible with the VHP resistant pump head
(MXPHEAVHP) only. These items are designed for use with Milliex® ltration devices only.
Millipore
VHP
ON
C
OK
START
OFF
Pump Body
VHP Resistant
Pump Head
Pump Head
Mounting Post
Control Panel
and Display
4
B. Manifold tray for VHP pumps (MXPTRAY03V2)
The manifold tray is used to assemble the pumps together.
C. Milliex®Plus pump VHP Hub kit (MXPHUBKIT)
The VHP Hub kit is composed of:
• Some components for the electrical parts: electrical hub, cables set and power supply
• Some components for the uidic parts: uidic hub and tubes set
MXPELEHUB
Milliflex®electrical
hub VHP compatible
MXPFHUVHP
Milliflex®fluidic hub
VHP compatible
MXPELCVHP—VHP
cables set for Milliflex®
electrical hub
MXTUBVHP—VHP
tubes set for Milliflex®
fluidic hub
MXPP0WVHP Electrical hub
power supply (with 1 power cord Eur
—1 power cord US)
5
D. Supply set for one VHP Pump (MXPSPL001)
The supply set is composed of:
• A power supply
• A uidic tube
5. System installation
A. Single pump system
Connect the supply set (uidic tube and power cable) to the VHP pump as follows:
Millipore
VHP
ON
C
OK
START
OFF
Then place the system in the isolator.
6
B. Three pump system
When using a three pump system, it is strongly recommended to assemble the pumps on the Manifold tray,
and to use the Hub kit for the electrical and uidic connections.
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
C
OK
START
OFF
It is recommended to assemble the pumps together before placing the system in the isolator. The use of
the tray facilitates the transfer of the assembled system to the isolator.
Caution: when assembled, the system is heavy (14.3 kg without the heads). Make sure you can handle the
system to transfer to the isolator.
1. Assembly of the 3 pumps on the tray
Do not place the pump head at this stage.
• Put the pump lead on each pump to protect them through the assembly step.
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
C
OK
START
OFF
7
• Reverse the 3 pumps: the keypad should be facing the operator and the pumps should be aligned to
enable assembly with the tray
• Put in place the tray
• Fix each pump one by one to the tray using the fast screw
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
VHP Resistant
8
• Once the 3 pumps are assembled on the tray, connect the electric cables and uidic tubes to each pump
Detail of the electrical connection:
• Once all the connections are in place, reverse the whole system using the manifold tray. Take care not to
crush the uidic tubes and electric cables while reversing the system.
VHP Resistant
VHP Resistant
VHP Resistant
9
VHP Resistant
VHP Resistant
VHP Resistant
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
C
OK
START
OFF
Millipore
VHP
ON
C
OK
START
OFF
1.
2.
3.
10
2. Hub installation
The VHP Compatible Milliex® PLUS Pump Hub is used to connect the uidic tubes and electrical cables from
up to three Milliex® PLUS pumps.
• Fluid Line Connections
Push the Milliex® PLUS Pump uid line connectors
into the uid hub until a click is heard. Install the
other end of the tubing onto the pumps.
Insert the output tubing onto the stainless
steel connector.
To disconnect the uid lines, push on the button
and pull the connector.
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