3D Histech PANNORAMIC SCAN RX Manuale utente

PANNORAMIC® SCAN RX

1.0

USER’S GUIDE

FOR RESEARCH USE ONLY. NOT FORUSE IN DIAGNOSTIC PROCEDURES.

May 13, 2021 –Rev.1

PANNORAMIC® SCAN RX 1.0

CONTENTS

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Contents

Contents 1

Disclaimer 4

Declaration of Conformity 6

About this User's Guide 7

Character Formats and Symbols 8

Notes Regarding Operational Safety 9

Notes on Warranty 13

Terms and Abbreviations 14

1Product Description 15

1.1 Product Overview 15

1.1.1 Intended Use 15

1.1.2 Features and Benefits 15

1.1.3 Warning and Information Labels 17

1.1.4 Base Unit 18

1.2 System Overview 19

1.2.1 Pannoramic® SCANRX system 19

1.2.2 Hardware Options 20

1.2.3 Control Software 22

2Installation 24

2.1 Operation System of the Control Computer 24

2.2 Control Computer Ports 26

2.3 Connectors and Cables 27

2.4 Coupling the Lumencor SOLA SM Unit with the Scanner 28

2.5 Coupling the Lumencor Spectra 6 Unit with the Scanner 28

2.6 External Power Supply Unit 29

2.7 Power the Scanner On/Off 29

3Operating Slides and Magazines 30

3.1 Preparing Slides and Magazines 30

3.2 Affixing Barcode Stickers to Slides 32

3.3 Inserting and Removing Slides 33

4Software Description 36

4.1 Starting/Exiting Pannoramic® Scanner Software for Research 36

PANNORAMIC® SCAN RX 1.0

CONTENTS

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

4.1.1 Starting theControl Software 36

4.1.2 Exiting Pannoramic® Scanner Software for Research control software 36

4.2 Main Window Functions 37

4.3 Hotkeys 55

5Scanning Modes and Settings 56

5.1 Brightfield Scanning Mode 56

5.1.1 Profile Settings Panel 57

5.1.2 Microscope Control Panel 64

5.1.3 Quick Preview Functions 75

5.1.4 Quick Microscope Functions 75

5.2 Fluorescence Microscope Mode 77

5.2.1 Profile Settings Panel 77

5.2.2 MicroscopeControl Panel 87

5.2.3 Hidden Functions 99

5.2.4 Quick Microscope Functions 100

5.2.5 Bottom Menu Bar of the Main Window 102

5.3 Planner Mode 103

5.3.1 General Functions at the Main Menu 103

5.3.2 General Functions at the Magazine Menu 106

5.3.3 General Functions at the Slide Menu 106

5.3.4 Slide View with Card 108

5.3.5 Table View Mode 110

5.3.6 Card Collection View Mode 111

5.4 Profile and Preview Overview on the Planner 112

5.5 Progress Features 113

6Settings and Services 114

6.1 Settings 114

6.2 Services 125

7Point Spread Function 134

8Using Profiles 136

9Troubleshooting and Maintenance 138

9.1 Activation of the Control Software 138

9.2 Recovery Functions 143

9.3 Safety Information 143

PANNORAMIC® SCAN RX 1.0

CONTENTS

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

9.3.1 Cleaning the Device 144

9.3.2 Cleaning the Magazines 145

9.3.3 Preventive Maintenance 145

9.4 Troubleshooting 145

9.4.1 Fluorescent Applications (Optional) 147

9.5 Maintenance 148

9.5.1 Removing the Protective Covers 148

9.5.2 Removing a Slide 149

9.5.3 Installing and Removing the Filter Module (Fluorescent Option) 151

9.5.4 Removing the Magazine from the Transporting System 153

9.5.5 Transporting Pannoramic® SCANRX 154

10 Technical Data 156

PANNORAMIC® SCAN RX 1.0

DISCLAIMER

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Disclaimer

Intellectual property related to the 3DHISTECH products are as follows:

•P1300124;PCT/HU2014/000020; EP 14745228.8.;US 14/771.380

•P0700404;PCT/HU2008/000065;EP 08762668.5.;US 12/663.537

•P1700279; PCT/HU2018/050030

•P1700483

•P1500394;PCT/HU2016/050039; EP 16840280.8.; US 15/756.370

•P0700409; US2008/0306964

•P0800181;PCT/HU2009/000027; EP 09721248.4.

•P0600435;PCT/HU2007/000047;EP 2024772;US 12/301.781

•P0600177;PCT/HU2007/000018; EP 1.994.398;US 12/281.566

•P0900741; PCT/HU2010/000130;EP 10812989.1.

•P0900142; PCT/HU2010/000027;EP 10726183.6

•P101036; PCT/IB2005/050351;EP 1789831; US7.663.078

•P0301911; PCT/HU04/00019;EP 1644767; US 7327515

The above mentioned granted patents, granted utilitymodel, registeredtrademarks,pending

internationaland national patent applications and the othercorresponding IP are the sole

properties of the 3DHISTECH Ltd.

3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to,

general or specificdamage, indirectdamage, consequentialdamageorincidentaldamage,

includingthe results of the analysis of the digitizedslides, forexample, change of health status

related to erroneous diagnosis from the digitized slide(s)) that stems from oris associated with

use of Product, digitized slides, quality of staining,quality of stainedslides, qualityof used

method of staining.3DHISTECHLtd. assumesno responsibility forthe functionalityand fault-

free condition of your “application programs” (Workflows, VBA macros, Commander scripts).

PANNORAMIC® SCAN RX 1.0

DISCLAIMER

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

CAUTION

For Research Use Only. Not for use in diagnosticprocedures. This product has not been approved

or cleared as a medical device by theU.S. Food and Drug Administration.

Do not use this devicein close proximity to sources of strong electromagneticradiation (e.g.,

unshielded intentional RF sources),as these may interfere with the proper operation.

Third-party disclaimer

3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to, general

or specificdamage, indirectdamage, consequentialdamage or incidentaldamage,including

damage resulting fromlost profits, interruptionof business,loss of business information,

pecuniary loss or similar damage) that stems fromor is associated with the incorporated part of

this Product that is made by a third-party company.

THE SOFTWARE IS PROVIDED “AS IS” AND WITHOUT WARRANTY OF ANY KIND, EXPRESSED,

IMPLIEDOR OTHERWISE, INCLUDING WITHOUTLIMITATION, ANY WARRANTY OF

MERCHANTABILITY OR FITNESS FOR A PARTICULARPURPOSE.

FurtherInformation

For the latest information on 3DHISTECH products and services, please visit our website at the

following URL: http://www.3dhistech.com.

Company Address

3 Öv Street, 1141 Budapest –HUNGARY

PANNORAMIC® SCAN RX 1.0

DECLARATION OF CONFORMITY

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Declaration of Conformity

3DHISTECH Ltd. declares that the product Pannoramic® SCANRX slide scanner is designedand

produced with considerationof specified requirements according to the standards listed below:

IEC 61010-1:2010, “Safety Requirements for Electrical Equipment for Measurement, Control, and

Laboratory Use –Part 1: General Requirements”

IEC 61010-2-081:2015, “Safety requirements for electrical equipment for measurement, control and

laboratory use –Part 2-081: Particular requirements for automatic and semi-automaticlaboratory

equipment for analysis andother purposes”

There is no further operator (user) action required in case of residual risks.

Further informationmay be obtained from the manufacturer:

3DHISTECH Ltd.

3 Öv Street

1141 Budapest –HUNGARY

PANNORAMIC® SCAN RX 1.0

ABOUT THIS USER'S GUIDE

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

About this User's Guide

The purposeof this manual is to assist the user in the safeand reliable operation of the product

described. Before operating thedevice, you must carefully read this instructionmanual, and

adhereto all WARNING and CAUTION notices (refer to chapter Notes RegardingOperational

Safety for more information), anda copy should be kept in the close to the scanner for reference

whenever required.

This User's Guide is a part of the Pannoramic® SCANRX system identified by the relevant article

numbers included in the 3DHISTECH OrderingGuide.

PANNORAMIC® SCAN RX 1.0

CHARACTER FORMATS AND SYMBOLS

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Character Formats and Symbols

The following character formats and symbols call your attentionin this manual:

Example (text in bold)

Words or charactersthat appear on thescreen. These include field names, screen and window

titles, push-buttonand menu names, paths or options.Keys on the keyboard.For example,

function keys (such as F11) or the Ctrl+Shotkey.

Example (text in bold and italics)

Cross-references withinthis document or to other documents.

Warning!

It might cause irreversible damage or harmto the user of the product or the product itself if

this instruction is not followed.

Caution!

It might cause the product to not work properly if this instruction is not followed and alerts

to a potential danger situation.

Notice:

Calls attention to some important features.

PANNORAMIC® SCAN RX 1.0

NOTES REGARDING OPERATIONAL SAFETY

MAY 13, 2021

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Notes Regarding Operational Safety

The below chapter of this User’s Guide contains information and warnings of a kind that must be

followed by owner/operator personnel.

Warning and advisorysymbols which are used on thebase unit of thePannoramic® SCANRX and

in chapter 1.1.3 Warning and InformationLabels havethefollowingmeanings:

Warning!

Disconnect mains plug! Remember to unplugthe power cord before you open the

Pannoramic® SCANRX main unit for maintenance.

Crush hazard! Thereis crush hazard in the movementarea of the slideinsert during

operation. Makesure not to reach with your hands into theinstrument to avoid the risk of

crushing your fingers. Please notethat thedigitizing process has to be interrupted and the

slide magazine moved via software to the output positionbefore removing it.

The Pannoramic® SCANRX, including anyof its originalaccessory components, should not be

operated in any other way than described in chapter1.1.1 IntendedUse.

Any of the following notesshould be strictly observed:

Warning!

If operating the device other than specified by the manufacturer,the levelof safety will

decrease.

Warning!

Insert the power cord plugs only into a grounding outlet. The protective action must not be

rendered ineffective by extension cables without protective conductor.The Pannoramic®

SCANRX has a built-in protection which mustnot berendered ineffectiveby extension

cables without protective (earth-ground) conductor.

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