Purigen Ionic Manuale utente

Purigen Biosystems, Inc.

5700 Stoneridge Drive, Suite 100

Pleasanton, CA 94588

TEL: +1 877 787-4436 EMAIL: [email protected]

NUCLEIC ACID PURIFICATION – PURE AND SIMPLE™

Ionic™ Puriﬁcation System

SITE PREP GUIDE

VERSION 3.0

PART NUMBER: PUR-DOC-1

NUCLEIC ACID PURIFICATION – PURE AND SIMPLE™

TOC

Support 4

Introduction 5

Additional Resources 5

Delivery and Installation 5

Box Dimensions and Contents 6

Laboratory Requirements 6

General Requirements 6

Instrument Dimensions 7

Placement Requirements 8

Lab Bench Guidelines 8

Vibration Guidelines 9

Electrical Requirements 9

Power Specifications 9

Recommendations 9

Power Cords 10

Fuses 10

Uninterruptible Power Supply 10

Product Certifications and Compliance 10

Environmental Considerations 11

Pre-Installation Checklist 12

Acknowledgment and Authorization 13

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IONIC™ PURIFICATION SYSTEM

document without the express written consent of Purigen Biosystems, Inc. is strictly forbidden. Nothing contained

herein shall constitute any warranty, express or implied, as to the performance of any products described herein.

Any and all warranties applicable to any products are set forth in the applicable terms and conditions of sale

accompanying the purchase of such product. Purigen Biosystems provides no warranty and hereby disclaims any

and all warranties as to the use of any third party products or protocols described herein. The use of products

described herein is subject to certain restrictions as set forth in the applicable terms and conditions of sale

accompanying the purchase of such product. “Ionic™” is a trademark of Purigen Biosystems, Inc. All other

trademarks are the property of their respective owners. All products and services described herein are intended FOR

RESEARCH USE ONLY and NOT FOR USE IN DIAGNOSTIC PROCEDURES.

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IONIC™ PURIFICATION SYSTEM

Support

For technical information or advice, please contact PurigenBiosystems Support at any time.

Phone: 1-877-PURIGEN (787-4436)

Email: support@purigenbio.com

PurigenBiosystems, Inc.

5700 Stoneridge Drive, Suite 100

Pleasanton, CA 94588

DOCUMENT NUMBER:PUR-DOC-1

FOR RESEARCH USE ONLY AND NOT FOR USE IN DIAGNOSTIC PROCEDURES.4

IONIC™ PURIFICATION SYSTEM

Introduction

This guide contains specifications and guidelines for preparing your site for installation and operation of the Ionic™

Purification System. Prior to installation of your Ionic system, a PurigenBiosystems Field Service Engineer (FSE) will

contact you to schedule the install and confirm that your site meets the preparation requirements described in this

document. If your system installation has already been scheduled, and you believe your site may not be ready in

time, please contact your PurigenBiosystems Field Service Engineer (FSE) for assistance.

Laboratory space requirements

Electrical requirements

Environmental constraints

Computing requirements

User-supplied consumables and equipment

Additional Resources

The following documentation is available for download from the PurigenBiosystems website.

Guide Name Description

Ionic™ Purification System

User Guide

Provides an overview of instrument components and software, and procedures for proper instrument

maintenance and troubleshooting.

Ionic™ Cells to Pure DNA Kit Provides steps to use the Protocol and instructions for the Cells to Pure DNAKit.

Ionic™ FFPE to Pure DNAKit Provides steps to use the Protocol and instructions for FFPEto Pure DNA Kit.

Table 1: Additional Documentation Resources

Delivery and Installation

Following your purchase of an Ionic system, a PurigenBiosystems representative will contact you to confirm receipt

of your order and provide an early estimate of delivery. Prior to delivery, a PurigenBiosystems FSE will contact you

to schedule the installation.

The Ionic system will be shipped to you directly. In this case, you will receive shipment tracking information from

PurigenBiosystems. Inspect the packages containing your Ionic system and report any signs of damage or rough

handling to your PurigenBiosystems Support.

I M P O R T A N T Do not unpack the instrument prior to installation. The system must be

unpacked by a PurigenBiosystems FSE during installation.

C A U T I O N Only PurigenBiosystems personnel can unpack, install, or move the instrument.

Mishandling of the instrument can affect the alignment or damage instrument components.

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IONIC™ PURIFICATION SYSTEM

C A U T I O N After your PurigenBiosystems representative has installed and prepared the

instrument, do not relocate the instrument. Moving the instrument improperly can affect the

alignment and compromise data integrity. If you want to relocate the instrument, contact your

PurigenBiosystems representative.

Box Dimensions and Contents

The Ionic system is shipped in a double-wall corrugated fiberboard box with a designer tray with full overlap, poly

straps and hand holds. Use the following dimensions to determine the minimum door width required to

accommodate the shipping container.

Measurement Box Dimensions

Height 62.7 cm (24.7 in.)

Width 47.2 cm (18.6 in.)

Depth 55.1 cm ( 21.7 in.)

Weight 29.0 kg (64 lbs.)

Table 2: Box Dimensions

The box contains the instrument along with the following components:

1 Power Cable

1 Leveling Plate

Laboratory Requirements

This section provides requirements and guidelines to set up your lab space for the Ionic system properly. For more

information, see "Environmental Considerations" on page11.

General Requirements

Adequate floor space near the installation site to accommodate the unpacking and unboxing of system

components.

Adequate clearance around the instrument for operator and service access.

Access to receptacle for power.

Rigid table or benchtop with the appropriate footprint and construction required to minimize unwanted

vibration or instability.

Adequate ventilation to accommodate heat output for all devices in the laboratory where system will be used.

Adequate management of the laboratory environment to minimize fluctuations in temperature and humidity.

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IONIC™ PURIFICATION SYSTEM

Instrument Dimensions

Figure 1: Instrument Dimensions with Leveling Plate (Front)

Figure 2: Instrument Dimensions with Leveling Plate (Side)

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IONIC™ PURIFICATION SYSTEM

The Ionic system must be placed on a leveling platform which is provided by PurigenBiosystems. The leveling

platform minimally increases the overall dimensions and weight.

The Ionic system has the following dimensions upon installation:

Measurement (with leveling plate) Instrument Dimensions

Width 43 cm (16.9 in.)

Depth 52 cm (20.5 in.)

Height 45 cm (17.7 in.)

Weight 24.5 kg (54.0 lbs.)

Table 3: Measurement with Leveling Plate

Placement Requirements

Select the installation location for your Ionic system prior to scheduled installation. The Ionic system must be

positioned to allow access to the power switch and power outlet, for proper ventilation, and for servicing the

instrument.

Make sure that you can reach around the left-side of the instrument to turn on or turn off the power switch on

the back panel adjacent to the power cord.

Position the instrument so that personnel can quickly disconnect the power cord from the outlet.

The instrument must be accessible from all sides using the following minimum clearance dimensions:

Access Minimum Clearance

Sides Allow at least 35 cm (14 in.) empty bench space to the left-hand or right-hand side of the instrument for pipettes, pipette tips,

reservoir, and keyboard.

Rear Allow at least 10.16 cm (4.0 in.) behind the instrument.

Top Allow at least 2 cm (0.79 in.) above the instrument. If the instrument is positioned under a shelf, make sure that the minimum

clearance requirement is met.

Table 4: Instrument Clearance Requirements

C A U T I O N If you need to relocate the Ionic system, contact your PurigenBiosystems

representative. Moving the instrument improperly can impact the alignment and compromise

data integrity.

C A U T I O N Heat generated by the instrument is expelled as hot air from the rear of the

instrument, which must not be blocked by any object closer than 10 cm to avoid potentially

dangerous overheating.

Lab Bench Guidelines

PurigenBiosystems recommends placing the instrument on a fixed lab bench or table capable of supporting an

instrument weighing 24.5 kg (54.0 lbs.) and with enough surface area to encompass the instrument and provide

adequate workspace for operators. Use of mobile tables or benches with casters should be avoided.

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IONIC™ PURIFICATION SYSTEM

N O T E Lysate preparation can occur on empty bench space, a separate benchtop, or in a BSL

hood.

Vibration Guidelines

C A U T I O N The Ionic system is sensitive to vibrations.

Use the following guidelines to minimize vibrations during runs and ensure optimal performance:

Place the instrument on a sturdy ,immobilized, surface that is isolated from nearby equipment or designed to

suppress the transmission of vibration from nearby equipment.

Do not place other equipment on the bench that produces vibrations, such as a shaker, vortexer, centrifuge,

freezer, or instruments with heavy fans.

Do not install the instrument near frequently used doors. Opening and closing of doors might induce

vibrations.

Do not install a keyboard tray that hangs below the bench.

Do not touch the instrument or open the reagent compartment during operation.

Do not place objects on top of the instrument.

Electrical Requirements

This section lists power specifications and describes electrical requirements for your facility.

Power Specifications

Type Specification

Line Voltage 110 - 120 VAC, 60 Hz, 2.5 A

Power Consumption 300 Watts

Table 5: Instrument Power Specifications

Recommendations

The following practices are recommended to ensure safe operation of the PurigenBiosystems Ionic system:

The instrument should be plugged into a receptacle on a dedicated circuit with proper voltage, amperage and

grounding.

A power line regulator is required if the voltage fluctuates in excess of +/- 10% of the normal voltage.

A surge protector is recommended in areas with frequent electrical storms or near electrically “noisy” devices

such as refrigerators or centrifuges.

Instrument must be placed less than 2 meters from a power outlet.

The power outlet must be accessible at all times for safety.

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IONIC™ PURIFICATION SYSTEM

Power Cords

Hazardous voltages are removed from the instrument only when the power cord is disconnected from the AC power

source.

The table below lists the specifications for the power cord included with the instrument.

Specification North America

Current Rating 10 A

Voltage Rating 125 VAC

Input Connection 1 NEMA 5-15P

Input Connection 2 IEC 320-C13

Cord Length 6.56' (2.00m)

Cord Type SJT

Table 6: Instrument Power Cord Specifications

W A R N I NG Never use an extension cord to connect the instrument to a power supply.

Fuses

The Ionic system contains no user-replacable fuses.

Uninterruptible Power Supply

PurigenBiosystems recommends the use of a user-supplied uninterruptible power supply (UPS). PurigenBiosystems

is not responsible for runs affected by interrupted power regardless of whether the instrument is on a UPS. Standard

generator-backed power is often not uninterruptible and a brief power outage occurs before power resumes, which

interrupts a run.

PurigenBiosystems recommends the use of a UPS rated at least 1500VA/750W with a total capacity of 300Wh to

avoid loss of sample and materials during a power outage (APC BX1500M 1500VA Back-UPS Pro, or similar).

Product Certifications and Compliance

The Ionic Purification System is certified to the following standards:

UL 61010-1, 3rd Edition

CAN/CSA C22.2 No. 61010-1-12, 3rd Edition

Subpart B of Part 15 of FCC Rules for Class A digital devices

ICES-003, Issue 6

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IONIC™ PURIFICATION SYSTEM

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